Bromelain belongs to a group of protein digesting enzymes obtained commercially from the fruit or stem of pineapple. Historically, natives of Central and South America used pineapple for a variety of ailments, such as digestive disorders.
Bromelain accounts for many therapeutic benefits like the treatment of angina pectoris, bronchitis, sinusitis, surgical trauma, and thrombophlebitis, debridement of wounds, and enhanced absorption of drugs, particularly antibiotics. It also relieves osteoarthritis, diarrhea, and various cardiovascular disorders. Topical (applied to the skin) bromelain is used for wounds and burns.
A systematic review of the evidence indicates that bromelain is helpful in relieving symptoms of acute nasal and sinus inflammation when used in combination with standard medications.